Expert Comments on Available Evidence
The DEPRESSD Project
A Unique and Rigorous Data Platform for Depression Screening Research
Peer-Reviewed Oral Conference Presentations
Negeri ZF, Levis B, Wu Y, Dendukuri N, Thombs BD, Benedetti A. Latent class models for individual participant data meta-analyses of the Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression. 2021 Annual Statistical Society of Canada Meeting. Canada, June 2021. (presented virtually due to COVID-19).
Negeri ZF, Levis B, Wu Y, Thombs BD, Benedetti A.. Latent class models for individual participant data meta-analyses of diagnostic test accuracy studies with imperfect reference standards. A day with... Statistical Methods Group (Cochrane Collaboration). United Kingdom. May 2021. (presented virtually due to COVID-19).
Levis B, Dehtiarova Y, Sun Y, Wu Y, Benedetti A, Thombs BD, and the DEPRESSD PHQ Collaboration. depressionscreening100.com/phq: a practice-based perspective to using the Patient Health Questionnaire-9 to screen for depression. 2020 Cochrane Colloquium. Toronto, Ontario, Canada. October 2020. [cancelled due to COVID-19].
Levis B, Negeri Z, Sun Y, Benedetti A, Thombs BD, and the DEPRESSD EPDS Collaboration. Screening for depression in pregnant and postpartum women: an individual participant data meta-analysis of the Edinburgh Postnatal Depression Scale. 2020 Cochrane Colloquium. Toronto, Ontario, Canada. October 2020. [cancelled due to COVID-19].
Levis B, Sun Y, He C, Wu Y, Krishnan A, Bhandari PM, Neupane D, Imran M, Brehaut E, Negeri ZF, Fischer FH, Benedetti A, Thombs BD, and the DEPRESSD PHQ Collaboration. Screening for depression with the Patient Health Questionnaire-2 (PHQ-2) alone and in combination with the PHQ-9: individual participant data meta-analysis. 2020 Cochrane Colloquium. Toronto, Ontario, Canada. October 2020. [cancelled due to COVID-19].
Negeri ZF, Levis B, Wu Y, Thombs BD, Benedetti A, and the DEPRESSD PHQ Collaboration. Latent class models for individual participant data meta-analyses of diagnostic test accuracy studies with imperfect reference standards. 2020 Cochrane Colloquium. Toronto, Ontario, Canada. October 2020. [cancelled due to COVID-19].
Negeri ZF, Levis B, Wu Y, Thombs BD, Benedetti A, and the DEPRESSD PHQ Collaboration. Latent class models for individual participant data meta-analyses of diagnostic test accuracy studies with imperfect reference standards. 2020 Joint Statistical Meetings (JSM). Philadelphia, Pennsylvania, USA, August 2020. [presented virtually due to COVID-19].
Wu Y, Levis B, Ioannidis JPA, Benedetti A, Thombs BD, DEPRESsion Screening Data (DEPRESSD) Collaboration. Major depression classification based on different diagnostic interviews: a synthesis of individual participant data meta-analyses. Methods for Evaluation of medical prediction Models, Tests and Biomarkers (MEMTAB) Conference. Leuven, Belgium. July 2020. [postponed due to COVID-19].
Bhandari PM, Levis B, Neupane D, Patten SB, Shrier I, Thombs BD, Benedetti A, and the DEPRESsion Screening Data (DEPRESSD) EPDS Collaboration. Bias in diagnostic accuracy estimates due to data-driven cutoff selection: simulation study using individual participant data from 49 studies on the diagnostic accuracy of the Edinburgh Postnatal Depression Scale. In Levis B (Chair). Use of individual participant data meta-analysis to address challenges in evaluating depression screening tool accuracy (Symposium). 81st Canadian Psychological Association Annual Convention. Montreal, Quebec, Canada. May 2020. [cancelled due to COVID-19].
Neupane D, Levis B, Bhandari PM, Thombs BD, Benedetti A, and the DEPRESsion Screening Data (DEPRESSD) EPDS and PHQ-9 Collaboration. Selective cutoff reporting in studies of the accuracy of the PHQ-9 and EPDS depression screening tools: comparison of results based on published cutoffs versus all cutoffs using individual participant data meta-analysis. In Levis B (Chair). Use of individual participant data meta-analysis to address challenges in evaluating depression screening tool accuracy (Symposium). 81st Canadian Psychological Association Annual Convention. Montreal, Quebec, Canada. May 2020. [cancelled due to COVID-19].
Wu Y, Levis B, Ioannidis JPA, Benedetti A, Thombs BD, and the DEPRESsion Screening Data (DEPRESSD) Collaboration. Major depression classification based on the SCID, CIDI and MINI diagnostic interviews: a meta-analysis of individual participant data meta-analyses. In Levis B (Chair). Use of individual participant data meta-analysis to address challenges in evaluating depression screening tool accuracy (Symposium). 81st Canadian Psychological Association Annual Convention. Montreal, Quebec, Canada. May 2020. [cancelled due to COVID-19].
Levis B, Bhandari PM, Neupane D, Thombs BD, Benedetti A, DEPRESsion Screening Data (DEPRESSD) PHQ Collaboration. Bias in diagnostic accuracy estimates due to data-driven cutoff selection: a simulation study. Methods for Evaluation of medical prediction Models, Tests and Biomarkers (MEMTAB) Conference. Leuven, Belgium. July 2020.
Neupane D, Levis B, Bhandari PM, Thombs BD, Benedetti A, DEPRESsion Screening Data (DEPRESSD) Collaboration. Selective cutoff reporting in diagnostic accuracy studies of the PHQ-9 and EPDS depression screening tools. In Wu Y (Chair). Addressing challenges in evaluating depression screening tool accuracy via individual participant data meta-analysis (Symposium). 9th Interdisciplinary Conference in Psychology (ICP). Ottawa, Canada. May 2020.
Bhandari PM, Levis B, Neupane D, Patten SB, Shrier I, Thombs BD, Benedetti A, and the DEPRESsion Screening Data (DEPRESSD) EPDS Collaboration. Bias in accuracy estimates from data-driven optimal cutoff selection: simulation study using EPDS IPDMA dataset. In Wu Y (Chair). Addressing challenges in evaluating depression screening tool accuracy via individual participant data meta-analysis (Symposium). 9th Interdisciplinary Conference in Psychology (ICP). Ottawa, Canada. May 2020.
Brehaut E, Neupane D, Bhandari PM, Levis B, Wu Y, Benedetti A, Thombs BD, DEPRESsion Screening Data (DEPRESSD) HADS Collaboration. Prevalence using the HADS Depression Subscale Compared to SCID Classification: Individual Participant Data Meta-Analysis. In Wu Y (Chair). Addressing challenges in evaluating depression screening tool accuracy via individual participant data meta-analysis (Symposium).
Wu Y, Levis B, Ioannidis JPA, Benedetti A, Thombs BD, DEPRESsion Screening Data (DEPRESSD) Collaboration. Major depression classification based on different diagnostic interviews: a synthesis of individual participant data meta-analyses. In Wu Y (Chair). Addressing challenges in evaluating depression screening tool accuracy via individual participant data meta-analysis (Symposium). 9th Interdisciplinary Conference in Psychology (ICP). Ottawa, Canada. May 2020.
Negeri ZF, Levis B, Benedetti A, Thombs BD, and the DEPRESsion Screening Data (DEPRESSD) PHQ Collaboration. Accuracy of the PHQ-9 for Screening to Detect Major Depression: Systematic Review and Meta-analysis of Individual Participant Data. In Wu Y (Chair). Addressing challenges in evaluating depression screening tool accuracy via individual participant data meta-analysis (Symposium). 9th Interdisciplinary Conference in Psychology (ICP). Ottawa, Canada. May 2020.
Levis B, Benedetti A, Rücker G, Jones HE, Thombs BD, and the DEPRESSD Collaboration. An empirical comparison of methods for meta-analysis of diagnostic accuracy when studies selectively report cutoffs. 40th Annual Conference of the International Society for Clinical Biostatistics. Leuven, Belgium. July 2019.
Levis B, Benedetti A, Rücker G, Jones HE, Thombs BD, and the DEPRESSD Collaboration. An empirical comparison of methods for meta-analysis of diagnostic accuracy when studies selectively report cutoffs. 40th Annual Conference of the International Society for Clinical Biostatistics. Leuven, Belgium. July 2019.
Wu Y, Levis B, Thombs BD, Benedetti A, and the DEPRESsion Screening Data (DEPRESSD) Collaboration. Evaluation of the equivalency of the PHQ-8 and PHQ-9: A systematic review and individual participant data meta-analysis. McGill Epidemiology, Biostatistics and Occupational Health 12th Annual Student Research Day. Montreal, Quebec, Canada. March 2019.
Levis B, Rücker G, Jones HE, Thombs BD, Benedetti A, and the DEPRESSD Research Group. Estimating diagnostic accuracy when primary studies selectively report cutoffs: Individual participant data meta-analysis versus three methods for analyzing published data. 2018 Cochrane Colloquium. Edinburgh, Scotland. September 2018.
Levis B, Rücker G, Jones HE, Thombs BD, Benedetti A, and the DEPRESSD Research Group. Estimating diagnostic test accuracy in the context of incomplete reporting across cutoff thresholds: A comparison of conventional meta-analysis of published data, two modelling approaches using published data, and individual participant data meta-analysis. Methods for Evaluating Medical Tests and Biomarkers (MEMTAB) Conference. Utrecht, Netherlands. July 2018.
Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti M, Sanchez TA, Thombs BD, and the DEPRESSD Research Group. Diagnostic accuracy of the PHQ-9 depression screening tool compared to semi-structured versus fully structured diagnostic interviews for major depression: An individual participant data meta-analysis comparing reference standards. Ninth Annual Lady Davis Institute for Medical Research Scientific Retreat. Montreal, Quebec, Canada. May 2018.
Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti M, Sanchez TA, Thombs BD, and the DEPRESSD Research Group. Diagnostic accuracy of the PHQ-9 depression screening tool compared to semi-structured versus fully structured diagnostic interview reference standards: An individual participant data meta-analysis. McGill Epidemiology, Biostatistics and Occupational Health 11th Annual Student Research Day. Montreal, Quebec, Canada. March 2018.
Harel D, Ishihara M, Levis B, Thombs BD. Optimal methods for shortening patient-reported outcome measures. International Conference on Health Policy Statistics, Charleston, SC, USA. January 2018.
Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti M, Thombs BD, and the DEPRESSD Research Group. Overdiagnosis of major depression based on lay-administered fully structured diagnostic interviews. Preventing Overdiagnosis 2017. Quebec City, Quebec, Canada. August 2017.
Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti M, Thombs BD, and the DEPRESSD Research Group. Underestimation of depression screening tool sensitivity when using lay-administered fully structured diagnostic interviews as the reference standard: an individual patient data meta-analysis. Cochrane Canada Symposium. Hamilton, Ontario, Canada. May 2017.
Levis B, Benedetti A, Riehm KE, Saadat N, Levis AW, Azar M, Rice DB, Chiovitti M, Thombs BD, and the DEPRESSD Research Group. Diagnostic interviews for major depression: A comparison of diagnoses made using semi-structured vs. fully structured clinical interviews. McGill Epidemiology, Biostatistics and Occupational Health 11th Annual Student Research Day. Montreal, Quebec, Canada. April 2017.
Levis B, Benedetti A, Thombs BD. Selective cutoff reporting in diagnostic test accuracy studies of depression screening tools: Comparing traditional meta-analysis to individual patient data meta-analysis. 2015 Cochrane Colloquium. Vienna, Austria. October 2015.
Levis B, Benedetti A, Thombs BD. Selective cutoff reporting in studies of diagnostic test accuracy of depression screening tools: Comparing traditional meta-analysis to individual patient data meta-analysis. Preventing Overdiagnosis 2015. Bethesda, Maryland, USA. September 2015.
Levis B, Benedetti A, Levis AW, Thombs BD. Selective reporting in studies of diagnostic test accuracy: Comparing traditional meta-analysis to individual patient data meta-analysis to assess the diagnostic accuracy of the Patient Health Questionnaire-9. In symposium (BD Thombs, Chair), Improving evidence-based psychological services by identifying and reducing reporting biases. 76th Canadian Psychological Association Annual Convention. Ottawa, Ontario, Canada. June 2015.
Simoneau G, Levis B, Thombs BD, Benedetti A. An empirical comparison of methods to meta-analyze individual patient data of diagnostic accuracy. Statistical Society of Canada (SSC) Student Annual Conference. Halifax, Nova Scotia, Canada. June 2015.
Levis B. Selective cutoff reporting in studies of diagnostic accuracy of depression screening tools: Comparing traditional meta-analysis to individual patient data meta-analysis. McGill Epidemiology, Biostatistics and Occupational Health 11th Annual Student Research Day. Montreal, Quebec, Canada. April 2015.
Levis B, Thombs BD. Individual Patient Data (IPD) meta-analysis to overcome shortcomings in traditional meta-analysis of screening test accuracy. 74th Canadian Psychological Association Annual Convention. Quebec City, Quebec, Canada. June 2013.