Meet our team
DEPRESSD is an international collaborative project involving experts in health policy, psychiatry and statistics as well as investigators who have collected depression screening data. Our mission is to synthesize the global depression screening data in order to develop and apply rigourous methods on assessing depression screening tool accuracy that minimize bias and provide evidence to inform research and policy to improve mental health care. The project builds a database for shared usage and also provides a unique platform for trainee development, including skills in evidence synthesis and statistical modelling.
Congratulations to Dr. Zelalem Negeri and the DEPRESSD Team on their publication in The BMJ!
We are happy to share that the DEPRESSD Team's updated IPDMA on the accuracy of the PHQ-9 screening tool has been published in the BMJ. The project, led by Dr. Zelalem Negeri, combined individual participant data from 100 studies (>44,000 participants) to evaluate the screening accuracy of the PHQ-9. The combined sensitivity and specificity of the PHQ-9 were maximized at a cut-off of >=10. Specificity was similar across reference standards, but sensitivity in studies with semi-structured interviews was higher than with fully structured reference standards and with the MINI. Moreover, specificity was higher for men and older participants. The full article can be accessed here. Researchers and clinicians can use our results to determine outcomes, such as the total number of positive screens and false-positive screens, at different PHQ-9 cut-offs for different clinical settings as described in our knowledge translation tool here.
COVID-MINDS Interview with Dr. Thombs
See Q & A with Dr. Brett Thombs and COVID-MINDS on mental health research in the COVID-19 pandemic. Dr. Thombs discusses our living systematic review and what we have learned conducting this work: [LINK]
Congratulations to the COVID-19 Living Systematic Review (LSR) Team on receiving new CIHR funding!
We are excited to share that our LSR team was awarded a one-year grant ($220,052) by CIHR’s Emerging COVID-19 Research Gaps and Priorities Funding Opportunity for conducting our project “Mental Health during the COVID-19 Pandemic: An Ongoing Living Systematic Review of Mental Health Burden and Intervention Effectiveness to Inform Management Strategies During and Post-COVID-19.” This will allow the team to continue to update its synthesis of evidence on mental health in COVID-19.
Congratulations to the DEPRESSD team on receiving a new CIHR grant!
We are excited to share that the DEPRESSD team was awarded a 3-year grant ($279,224) by CIHR to develop and test statistical methods for individual participant data meta-analysis in diagnostic test accuracy. A special thank you to Dr. Yin Wu, Dr. Zelalem Negeri, Sheryl Sun and Dr. Brooke Levis, who worked closely with Dr. Andrea Benedetti on the CIHR funding competition!
Congratulations to Dr. Brett Thombs who has been awarded the Scleroderma Foundation’s 2021 “Messenger of Hope” award!
We are excited to share that Dr. Brett Thombs has just been awarded the Scleroderma Foundation’s 2021 “Messenger of Hope” award. This award was presented to Brett in recognition of his tremendous work with the scleroderma community through the SPIN programs that have elevated disease awareness, strengthened self-care among individuals living with the disease. Brett received this award on Saturday evening, July 17 in a virtual awards ceremony as part of the 2021 National Scleroderma Conference. Click HERE to watch the ceremony.
Article by Danielle Rice and Dr. Thombs on Depression Screening Published in BMJ!
We are excited to share that “Uncertainties Page” article by Danielle Rice and Dr. Thombs on depression screening evidence and what clinicians should do given there is not trial evidence to support screening was published today in BMJ. See the article here.
Preprints of Living Systematic Review of Mental Health in COVID-19 are available on MedRxiv
We are happy to share that the LSR COVID-19 project has 3 preprints published on MedRxiv:
Effects of COVID-19 Mental Health Interventions among Community-based Children, Adolescents, and Adults: A Living Systematic Review of Randomised Controlled Trials [LINK]
Comparison of Mental Health Symptoms prior to and during COVID-19: Evidence from a Living Systematic Review and Meta-analysis [LINK]
Comparison of Mental Health Symptom Changes from pre-COVID-19 to COVID-19 by Sex or Gender: A Systematic Review and Meta-analysis [LINK]
First DEPRESSD webinar recording is now AVAILABLE online
Yesterday, 35 collaborators attended the first DEPRESSD webinar - Addressing overestimation of prevalence based on self-report questionnaires: Are there cost-effective alternatives. For those of you who couldn’t make it to the meeting, you can watch the recording here [LINK]. The DEPREESSD team is planning to have more webinars later in the fall. We will keep you all posted. Thanks to all of you for your collaboration!
DEPRESSD Team published a new IPDMA protocol - Equivalence of the Accuracy of 9 and 10 item Versions of the Edinburgh Postnatal Depression Scale for Screening to Detect Major Depression among Pregnant and Postpartum Women on OSF
Dr. Xia Qiu, a visiting PhD Student, and the DEPRESSD team published their protocol on OSF. The objectives of the study are (1) to evaluate the equivalence of continuous EPDS-9 and full EPDS scores for assessing depressive symptom severity; and (2) to assess the equivalence of the accuracy of the EPDS-9 and full EPDS across relevant cut-offs for screening to detect major depression. Read more here.
Welcome new team member!
Suiqiong Fan, as a Research and Synthesis Analytical Coordinator, will be joining the DEPRESSD and COVID-19 Living Systematic Review projects on June 21. Suiqiong completed her BSc in Global Health at Wuhan University in 2019 and recently completed her MSc in Public Health from McGill. At McGill, Suiqiong worked on two projects related to child marriage. We’re fortunate to have her join the team! Click here to know more about her.
FIRST DEPRESSD Webinar - Addressing overestimation of prevalence based on self-report questionnaires: Are there cost-effective alternatives?
We are planning to host a series of webinars for project collaborators and other interested researchers and clinicians. Please see below for information regarding our FIRST WEBINAR [see our flyer]:
Dipika Neupane, Analytical Coordinator at the Lady Davis Institute of Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
Brooke Levis, Postdoctoral Research Fellow at the Centre for Prognosis Research, Keele University, Staffordshire, UK
16 June 2021 12:00-1:00 pm EST
HOW TO JOIN:
No need to register; simply click on the following link and enter the passcode:
Join Zoom Meeting